| 9/3/2022 | Centre (6-4) | at | Hanover | Suspended 10-13 in q3 | SAA | |||
| 9/4/2022 | Centre (6-4) | 31 | at | Hanover | 29 | SAA | ||
| 9/10/2022 | Hanover | 0 | at | Adrian (6-4) | 33 | at MIAA | ||
| 9/17/2022 | Olivet (5-5) | 31 | at | Hanover | 28 | MIAA | ||
| 10/1/2022 | Hanover | 37 | at | Defiance (3-7,3-4) | 20 | |||
| 10/8/2022 | Bluffton (2-8,2-5) | 21 | at | Hanover | 63 | |||
| 10/15/2022 | Hanover | 51 | at | Manchester (1-9,0-7) | 20 | |||
| 10/22/2022 | Mt St Joseph (10-1,7-0) | 44 | at | Hanover | 29 | |||
| 10/29/2022 | Hanover | 62 | at | Anderson (1-9,1-6) | 3 | |||
| 11/5/2022 | Rose-Hulman (6-4,6-1) | 47 | at | Hanover | 17 | |||
| 11/12/2022 | Hanover | 24 | at | Franklin (4-6,4-3) | 3 |
| vs Hanover | vs Other Opponents | Hanover compared to OOs | |
| Record: | 5-5 | 44-56 | |
| Points Scored: | 25.30 | 27.93 | 2.63 |
| Points Allowed: | 34.00 | 30.76 | 3.24 |
| Margin: | -8.70 | -2.83 | 5.87 |
| Total Points: | 59.30 | 58.69 | 0.61 |