| 9/3/2022 | Dubuque | 13 | at | Marietta (6-4) | 14 | at OAC | ||
| 9/10/2022 | Wisconsin-La Crosse (9-2) | 30 | at | Dubuque | 3 | WIAC | ||
| 9/17/2022 | Dubuque | 48 | at | Nebraska Wesleyan (1-9,0-8) | 34 | |||
| 9/24/2022 | Wartburg (13-1,8-0) | 25 | at | Dubuque | 0 | |||
| 10/1/2022 | Dubuque | 46 | at | Buena Vista (4-6,3-5) | 16 | |||
| 10/8/2022 | Simpson (1-9,1-7) | 14 | at | Dubuque | 66 | |||
| 10/15/2022 | Dubuque | 15 | at | Coe (7-3,6-2) | 14 | |||
| 10/22/2022 | Luther (2-8,2-6) | 7 | at | Dubuque | 68 | |||
| 11/5/2022 | Dubuque | 27 | at | Loras (5-5,5-3) | 20 | OT | ||
| 11/12/2022 | Central IA (7-3,5-3) | 24 | at | Dubuque | 21 |
| vs Dubuque | vs Other Opponents | Dubuque compared to OOs | |
| Record: | 4-6 | 51-44 | |
| Points Scored: | 19.80 | 31.52 | 11.72 |
| Points Allowed: | 30.70 | 29.29 | 1.41 |
| Margin: | -10.90 | 2.23 | 13.13 |
| Total Points: | 50.50 | 60.81 | -10.31 |