| 9/3/2022 | Wittenberg (5-5) | 28 | at | Cortland | 48 | NCA | ||
| 9/10/2022 | New Jersey (3-6) | 7 | at | Cortland | 63 | NJAC | ||
| 9/17/2022 | Cortland | 66 | at | Buffalo State (0-10) | 7 | at LL | ||
| 10/1/2022 | Morrisville (7-4,3-3) | 7 | at | Cortland | 28 | |||
| 10/8/2022 | Cortland | 42 | at | Brockport State (7-3,4-2) | 24 | |||
| 10/15/2022 | Hartwick (2-8,0-6) | 7 | at | Cortland | 69 | |||
| 10/22/2022 | Cortland | 48 | at | Utica (10-2,5-1) | 21 | |||
| 10/29/2022 | Cortland | 31 | at | Alfred (2-8,1-5) | 8 | |||
| 11/5/2022 | St John Fisher (4-6,2-4) | 14 | at | Cortland | 56 | |||
| 11/12/2022 | Cortland | 17 | vs | Ithaca (12-1) | 34 | Bronx NY | vs LL | |
| 11/19/2022 | Cortland | 28 | at | Randolph-Macon (11-1) | 35 | D3 Championship Round 1 | at ODC |
| vs Cortland | vs Other Opponents | Cortland compared to OOs | |
| Record: | 2-9 | 61-45 | |
| Points Scored: | 17.45 | 25.53 | 8.08 |
| Points Allowed: | 45.09 | 21.42 | 23.67 |
| Margin: | -27.64 | 4.11 | 31.75 |
| Total Points: | 62.54 | 46.95 | 15.59 |