| 9/3/2022 | Misericordia (3-7) | 14 | at | Alfred State | 17 | MidAC | ||
| 9/10/2022 | Rochester (3-7) | 30 | at | Alfred State | 17 | LL | ||
| 9/17/2022 | Alfred State | 17 | at | Husson (5-6) | 23 | at CCF | ||
| 9/24/2022 | Defiance (3-7) | 33 | at | Alfred State | 42 | HCA | ||
| 10/1/2022 | Alfred State | 30 | at | Anna Maria (5-4,3-3) | 25 | |||
| 10/8/2022 | Keystone (3-7,3-3) | 33 | at | Alfred State | 42 | |||
| 10/22/2022 | Dean (1-9,1-5) | 36 | at | Alfred State | 35 | OT | ||
| 10/29/2022 | Alfred State | 13 | at | Castleton State (5-5,4-2) | 37 | |||
| 11/5/2022 | Gallaudet (7-3,5-1) | 36 | at | Alfred State | 22 | |||
| 11/12/2022 | Alfred State | 48 | at | SUNY-Maritime (3-7,2-4) | 21 |
| vs Alfred State | vs Other Opponents | Alfred State compared to OOs | |
| Record: | 5-5 | 33-57 | |
| Points Scored: | 28.80 | 22.11 | -6.69 |
| Points Allowed: | 28.30 | 31.43 | -3.13 |
| Margin: | 0.50 | -9.32 | -9.82 |
| Total Points: | 57.10 | 53.54 | 3.56 |