| 9/3/2022 | Castleton State | 7 | at | Plymouth State (9-2) | 20 | at MSCAC | ||
| 9/10/2022 | Fitchburg State (1-9) | 0 | at | Castleton State | 48 | MSCAC | ||
| 9/17/2022 | Castleton State | 21 | at | Norwich (3-7) | 26 | at NEWMAC | ||
| 9/24/2022 | St Lawrence (4-6) | 34 | at | Castleton State | 6 | LL | ||
| 10/1/2022 | Dean (1-9,1-5) | 0 | at | Castleton State | 39 | |||
| 10/8/2022 | Castleton State | 17 | at | Gallaudet (7-3,5-1) | 20 | |||
| 10/15/2022 | SUNY-Maritime (3-7,2-4) | 33 | at | Castleton State | 36 | |||
| 10/22/2022 | Castleton State | 35 | at | Keystone (3-7,3-3) | 20 | |||
| 10/29/2022 | Alfred State (5-5,3-3) | 13 | at | Castleton State | 37 | |||
| 11/12/2022 | Castleton State | 26 | at | Anna Maria (5-4,3-3) | 27 | OT |
| vs Castleton State | vs Other Opponents | Castleton State compared to OOs | |
| Record: | 5-5 | 36-54 | |
| Points Scored: | 19.30 | 23.41 | 4.11 |
| Points Allowed: | 27.20 | 32.04 | -4.84 |
| Margin: | -7.90 | -8.63 | -0.73 |
| Total Points: | 46.50 | 55.45 | -8.95 |