| 9/3/2022 | Fort Lauderdale (0-2) | 2 | at | Erskine | 49 | None (Unk?) | ||
| 9/10/2022 | Erskine | 23 | at | Clark Atlanta (3-7) | 19 | at SIAC | ||
| 9/17/2022 | Lenoir-Rhyne (8-3,7-2) | 42 | at | Erskine | 20 | |||
| 9/24/2022 | Erskine | 14 | at | Newberry (9-2,7-2) | 32 | |||
| 10/1/2022 | Wingate (11-3,7-2) | 31 | at | Erskine | 7 | |||
| 10/8/2022 | Mars Hill (7-3,7-2) | 33 | at | Erskine | 13 | |||
| 10/15/2022 | Erskine | 0 | at | Carson-Newman (6-5,5-4) | 37 | |||
| 10/22/2022 | Virginia-Wise (2-9,1-8) | 28 | at | Erskine | 13 | |||
| 10/29/2022 | Erskine | 14 | at | Tusculum (8-3,6-3) | 49 | |||
| 11/5/2022 | Emory & Henry (5-6,4-5) | 32 | at | Erskine | 0 | |||
| 11/12/2022 | Erskine | 22 | at | Barton (4-7,3-6) | 51 |
| vs Erskine | vs Other Opponents | Erskine compared to OOs | |
| Record: | 9-2 | 54-48 | |
| Points Scored: | 32.36 | 25.22 | -7.14 |
| Points Allowed: | 15.91 | 23.50 | -7.59 |
| Margin: | 16.45 | 1.72 | -14.73 |
| Total Points: | 48.27 | 48.72 | -0.45 |