| 9/1/2022 | Virginia U-Lynchburg (0-10) | 0 | at | Virginia Union | 77 | None (Unk?) | ||
| 9/10/2022 | Virginia Union | 45 | at | Valdosta State (5-6) | 40 | at GSC | ||
| 9/17/2022 | Livingstone (4-6,4-5) | 6 | at | Virginia Union | 42 | |||
| 9/24/2022 | Virginia Union | 31 | at | Fayetteville State (9-3,8-1) | 28 | |||
| 10/1/2022 | St Augustine's (1-9,1-7) | 0 | at | Virginia Union | 69 | |||
| 10/8/2022 | Elizabeth City State (2-8,2-7) | 0 | at | Virginia Union | 49 | |||
| 10/15/2022 | Virginia Union | 27 | at | Bowie State (6-4,5-3) | 24 | OT | ||
| 10/22/2022 | Virginia Union | 45 | at | Lincoln PA (2-7,1-6) | 20 | |||
| 10/29/2022 | Chowan (7-4,7-2) | 26 | at | Virginia Union | 21 | |||
| 11/5/2022 | Virginia Union | 33 | at | Virginia State (6-4,5-3) | 21 | |||
| 11/19/2022 | Wingate (11-3) | 32 | at | Virginia Union | 7 | D2 Championship Round 1 | SAC |
| vs Virginia Union | vs Other Opponents | Virginia Union compared to OOs | |
| Record: | 2-9 | 51-55 | |
| Points Scored: | 17.91 | 22.26 | 4.35 |
| Points Allowed: | 40.55 | 26.91 | 13.64 |
| Margin: | -22.64 | -4.65 | 17.99 |
| Total Points: | 58.46 | 49.17 | 9.29 |