| 9/3/2022 | New Haven (8-3) | 20 | at | Bowie State | 27 | NE10 | ||
| 9/10/2022 | Bowie State | 12 | at | Saginaw Valley State (8-3) | 40 | at GLIAC | ||
| 9/17/2022 | Bowie State | 14 | at | Shaw (4-6,4-4) | 17 | |||
| 9/24/2022 | Bowie State | 36 | at | St Augustine's (1-9,1-7) | 20 | |||
| 10/1/2022 | Livingstone (4-6,4-5) | 7 | at | Bowie State | 53 | |||
| 10/8/2022 | Bowie State | 41 | at | Virginia State (6-4,5-3) | 14 | |||
| 10/15/2022 | Virginia Union (9-2,7-1) | 27 | at | Bowie State | 24 | OT | ||
| 10/22/2022 | Chowan (7-4,7-2) | 21 | at | Bowie State | 15 | |||
| 10/29/2022 | Bowie State | 36 | at | Elizabeth City State (2-8,2-7) | 29 | |||
| 11/5/2022 | Lincoln PA (2-7,1-6) | 24 | at | Bowie State | 41 |
| vs Bowie State | vs Other Opponents | Bowie State compared to OOs | |
| Record: | 4-6 | 47-46 | |
| Points Scored: | 21.90 | 25.05 | 3.15 |
| Points Allowed: | 29.90 | 25.11 | 4.79 |
| Margin: | -8.00 | -0.06 | 7.94 |
| Total Points: | 51.80 | 50.16 | 1.64 |