| 9/3/2022 | Virginia State | 19 | at | Lenoir-Rhyne (8-3) | 38 | at SAC | ||
| 9/10/2022 | Bluefield St WV (3-4) | 7 | at | Virginia State | 28 | D2Ind | ||
| 9/17/2022 | St Augustine's (1-9,1-7) | 7 | at | Virginia State | 42 | |||
| 9/24/2022 | Virginia State | 37 | at | Livingstone (4-6,4-5) | 7 | |||
| 10/1/2022 | Shaw (4-6,4-4) | 24 | at | Virginia State | 28 | |||
| 10/8/2022 | Bowie State (6-4,5-3) | 41 | at | Virginia State | 14 | |||
| 10/15/2022 | Virginia State | 40 | at | Chowan (7-4,7-2) | 43 | |||
| 10/22/2022 | Virginia State | 34 | at | Elizabeth City State (2-8,2-7) | 12 | |||
| 10/29/2022 | Virginia State | 42 | at | Lincoln PA (2-7,1-6) | 21 | |||
| 11/5/2022 | Virginia Union (9-2,7-1) | 33 | at | Virginia State | 21 |
| vs Virginia State | vs Other Opponents | Virginia State compared to OOs | |
| Record: | 4-6 | 42-47 | |
| Points Scored: | 23.30 | 23.54 | 0.24 |
| Points Allowed: | 30.50 | 26.40 | 4.10 |
| Margin: | -7.20 | -2.86 | 4.34 |
| Total Points: | 53.80 | 49.94 | 3.86 |