| 9/3/2022 | Elizabeth City State | 14 | at | Benedict (11-1) | 58 | at SIAC | ||
| 9/10/2022 | Livingstone (4-6,4-5) | 19 | vs | Elizabeth City State | 0 | Rocky Mount NC | ||
| 9/17/2022 | Winston-Salem State (3-6,3-4) | 17 | at | Elizabeth City State | 20 | |||
| 9/24/2022 | Elizabeth City State | 16 | at | Shaw (4-6,4-4) | 35 | |||
| 9/29/2022 | Elizabeth City State | 14 | at | Johnson C Smith (2-7,2-6) | 49 | |||
| 10/8/2022 | Elizabeth City State | 0 | at | Virginia Union (9-2,7-1) | 49 | |||
| 10/15/2022 | Lincoln PA (2-7,1-6) | 19 | at | Elizabeth City State | 21 | |||
| 10/22/2022 | Virginia State (6-4,5-3) | 34 | at | Elizabeth City State | 12 | |||
| 10/29/2022 | Bowie State (6-4,5-3) | 36 | at | Elizabeth City State | 29 | |||
| 11/5/2022 | Elizabeth City State | 8 | at | Chowan (7-4,7-2) | 54 |
| vs Elizabeth City State | vs Other Opponents | Elizabeth City State compared to OOs | |
| Record: | 8-2 | 46-45 | |
| Points Scored: | 37.00 | 24.96 | -12.04 |
| Points Allowed: | 13.40 | 22.89 | -9.49 |
| Margin: | 23.60 | 2.07 | -21.53 |
| Total Points: | 50.40 | 47.85 | 2.55 |