| 9/1/2022 | Virginia U-Lynchburg | 0 | at | Virginia Union (9-2) | 77 | at CIAA | ||
| 9/10/2022 | Virginia U-Lynchburg | 13 | at | Presbyterian (1-10) | 21 | at Pio | ||
| 9/17/2022 | Virginia U-Lynchburg | 19 | at | Delaware State (5-6) | 35 | at MEAC | ||
| 9/24/2022 | Virginia U-Lynchburg | 14 | at | North Carolina Central (10-2) | 59 | at MEAC | ||
| 10/1/2022 | Virginia U-Lynchburg | 10 | at | Morgan State (4-7) | 44 | at MEAC | ||
| 10/8/2022 | Virginia U-Lynchburg | 14 | at | Savannah State (5-5) | 28 | at SIAC | ||
| 10/15/2022 | Virginia U-Lynchburg | 0 | at | South Carolina State (3-8) | 36 | at MEAC | ||
| 10/22/2022 | Virginia U-Lynchburg | 7 | at | Southern (7-5) | 51 | at SWAC | ||
| 10/29/2022 | Virginia U-Lynchburg | 20 | at | Webber International (4-4) | 38 | at Sun | ||
| 11/12/2022 | Virginia U-Lynchburg | 0 | at | The Citadel (4-7) | 66 | at SoCon |
| vs Virginia U-Lynchburg | vs Other Opponents | Virginia U-Lynchburg compared to OOs | |
| Record: | 10-0 | 42-56 | |
| Points Scored: | 45.50 | 24.02 | -21.48 |
| Points Allowed: | 9.70 | 27.86 | -18.16 |
| Margin: | 35.80 | -3.84 | -39.64 |
| Total Points: | 55.20 | 51.88 | 3.32 |