| 9/1/2022 | Arkansas-Monticello | 40 | at | Southern Nazarene (5-6,5-6) | 26 | | | |
| 9/10/2022 | Oklahoma Baptist (1-10,1-10) | 17 | at | Arkansas-Monticello | 40 | | | |
| 9/17/2022 | Arkansas-Monticello | 27 | at | Henderson State (8-3,8-3) | 37 | | | |
| 9/24/2022 | Arkansas Tech (5-6,5-6) | 14 | at | Arkansas-Monticello | 35 | | | |
| 10/1/2022 | Arkansas-Monticello | 27 | at | Southwestern Oklahoma State (4-7,4-7) | 37 | | | |
| 10/8/2022 | Northwestern Oklahoma State (1-10,1-10) | 26 | at | Arkansas-Monticello | 23 | | | |
| 10/15/2022 | Arkansas-Monticello | 7 | at | Ouachita (11-1,11-0) | 41 | | | |
| 10/22/2022 | Harding (9-2,9-2) | 56 | at | Arkansas-Monticello | 43 | | | |
| 10/29/2022 | Southeastern Oklahoma State (6-6,6-5) | 48 | at | Arkansas-Monticello | 20 | | | |
| 11/5/2022 | Arkansas-Monticello | 0 | at | East Central (9-3,8-3) | 16 | | | |
| 11/12/2022 | Southern Arkansas (5-6,5-6) | 20 | at | Arkansas-Monticello | 7 | | | |