| 9/3/2022 | Mercyhurst (2-9) | 45 | at | Alderson-Broaddus | 28 | | | PSAC |
| 9/8/2022 | Alderson-Broaddus | 17 | at | West Liberty (4-7,3-7) | 30 | | | |
| 9/17/2022 | Wheeling (7-4,6-4) | 56 | at | Alderson-Broaddus | 41 | | | |
| 9/24/2022 | Alderson-Broaddus | 7 | at | Charleston WV (6-5,6-4) | 62 | | | |
| 10/1/2022 | West Virginia State (7-4,6-4) | 30 | at | Alderson-Broaddus | 3 | | | |
| 10/6/2022 | Fairmont State (3-8,3-7) | 51 | at | Alderson-Broaddus | 7 | | | |
| 10/15/2022 | Alderson-Broaddus | 12 | at | Glenville State (7-4,6-4) | 31 | | | |
| 10/22/2022 | West Virginia Wesleyan (1-10,1-9) | 31 | at | Alderson-Broaddus | 30 | | | |
| 10/29/2022 | Alderson-Broaddus | 7 | at | Frostburg State (8-3,7-3) | 58 | | | |
| 11/5/2022 | Alderson-Broaddus | 13 | at | Concord (9-2,8-2) | 50 | | | |
| 11/12/2022 | Notre Dame OH (9-3,9-1) | 27 | at | Alderson-Broaddus | 3 | | | |