| 9/3/2022 | Wofford | 0 | at | Chattanooga (7-4,5-3) | 31 | |||
| 9/10/2022 | Elon (8-4) | 26 | at | Wofford | 0 | CAAF | ||
| 9/17/2022 | Wofford | 7 | at | Virginia Tech (3-8) | 27 | at ACC | ||
| 9/24/2022 | Wofford | 22 | at | Kennesaw St (5-6) | 24 | at ASUN | ||
| 10/1/2022 | Mercer (7-4,5-3) | 42 | at | Wofford | 7 | |||
| 10/8/2022 | Wofford | 14 | at | Samford (11-2,8-0) | 28 | |||
| 10/15/2022 | The Citadel (4-7,3-5) | 16 | at | Wofford | 31 | |||
| 10/29/2022 | East Tennessee St (3-8,1-7) | 41 | at | Wofford | 48 | |||
| 11/5/2022 | Wofford | 29 | at | Western Carolina (6-5,4-4) | 36 | |||
| 11/12/2022 | VMI (1-10,0-8) | 16 | at | Wofford | 34 | |||
| 11/19/2022 | Wofford | 28 | at | Furman (10-3,7-1) | 63 |
| vs Wofford | vs Other Opponents | Wofford compared to OOs | |
| Record: | 8-3 | 57-58 | |
| Points Scored: | 31.82 | 27.18 | -4.64 |
| Points Allowed: | 20.00 | 27.12 | -7.12 |
| Margin: | 11.82 | 0.06 | -11.76 |
| Total Points: | 51.82 | 54.30 | -2.48 |