| 9/3/2022 | Rutgers (4-8) | 22 | at | Boston College | 21 | B10 | ||
| 9/10/2022 | Boston College | 10 | at | Virginia Tech (3-8,1-6) | 27 | |||
| 9/17/2022 | Maine (2-9) | 17 | at | Boston College | 38 | CAAF (1AA) | ||
| 9/24/2022 | Boston College | 14 | at | Florida State (10-3,5-3) | 44 | |||
| 10/1/2022 | Louisville (8-5,4-4) | 33 | at | Boston College | 34 | |||
| 10/8/2022 | Clemson (11-3,9-0) | 31 | at | Boston College | 3 | |||
| 10/22/2022 | Boston College | 15 | at | Wake Forest (8-5,3-5) | 43 | |||
| 10/29/2022 | Boston College | 3 | at | Connecticut (6-7) | 13 | at Ind | ||
| 11/4/2022 | Duke (9-4,5-3) | 38 | at | Boston College | 31 | |||
| 11/12/2022 | Boston College | 21 | at | North Carolina State (8-5,4-4) | 20 | |||
| 11/19/2022 | Boston College | 0 | at | Notre Dame (9-4) | 44 | at ND | ||
| 11/26/2022 | Syracuse (7-6,4-4) | 32 | at | Boston College | 23 |
| vs Boston College | vs Other Opponents | Boston College compared to OOs | |
| Record: | 9-3 | 76-64 | |
| Points Scored: | 30.33 | 27.39 | -2.94 |
| Points Allowed: | 17.75 | 24.36 | -6.61 |
| Margin: | 12.58 | 3.03 | -9.55 |
| Total Points: | 48.08 | 51.75 | -3.67 |