| 9/3/2022 | Mercer (7-4) | 16 | at | Auburn | 42 | SoCon (1AA) | ||
| 9/10/2022 | San Jose State (7-5) | 16 | at | Auburn | 24 | MW | ||
| 9/17/2022 | Penn State (11-2) | 41 | at | Auburn | 12 | B10 | ||
| 9/24/2022 | Missouri (6-7,3-5) | 14 | at | Auburn | 17 | OT | ||
| 10/1/2022 | LSU (10-4,6-3) | 21 | at | Auburn | 17 | |||
| 10/8/2022 | Auburn | 10 | at | Georgia (15-0,9-0) | 42 | |||
| 10/15/2022 | Auburn | 34 | at | Mississippi (8-5,4-4) | 48 | |||
| 10/29/2022 | Arkansas (7-6,3-5) | 41 | at | Auburn | 27 | |||
| 11/5/2022 | Auburn | 33 | at | Mississippi State (9-4,4-4) | 39 | OT | ||
| 11/12/2022 | Texas A&M (5-7,2-6) | 10 | at | Auburn | 13 | |||
| 11/19/2022 | Western Kentucky (9-5) | 17 | at | Auburn | 41 | CUSA | ||
| 11/26/2022 | Auburn | 27 | at | Alabama (11-2,6-2) | 49 |
| vs Auburn | vs Other Opponents | Auburn compared to OOs | |
| Record: | 7-5 | 98-46 | |
| Points Scored: | 29.50 | 33.81 | 4.31 |
| Points Allowed: | 24.75 | 21.88 | 2.87 |
| Margin: | 4.75 | 11.93 | 7.18 |
| Total Points: | 54.25 | 55.69 | -1.44 |