D2
9 Jan 2023 21:04:24
| 9/1/2022 | Chadron State | 0 | at | Angelo State | 35 | | | RMAC |
| Central Washington | 20 | at | Ferris State | 36 | | | @ GLIAC |
| Eastern New Mexico | 34 | at | New Mexico Highlands | 18 | | | @ RMAC |
| Western Oregon | 5 | at | Weber State | 41 | | | @ BSky (1AA) |
| 9/3/2022 | Colorado State-Pueblo | 59 | at | Midwestern State | 27 | | | RMAC |
| North American U | 0 | at | Texas A&M-Kingsville | 60 | | | None (Unk?) |
| Southwest Baptist | 41 | at | Texas-Permian Basin | 17 | | | GLV |
| Western Colorado | 6 | at | West Texas A&M | 44 | | | RMAC |
| Adams State | 20 | at | Western New Mexico | 34 | | | RMAC |
| 9/10/2022 | West Texas A&M | 34 | at | Adams State | 19 | | | @ RMAC |
| Western New Mexico | 13 | at | Central Washington | 24 | | | |
| Angelo State | 30 | at | Colorado Mines | 27 | OT | | @ RMAC |
| Midwestern State | 28 | at | Eastern New Mexico | 14 | | | |
| Sul Ross State | 14 | at | Texas A&M-Kingsville | 35 | | | ASWC (D3) |
| Western Colorado | 31 | at | Texas-Permian Basin | 34 | | | RMAC |
| Lincoln CA | 10 | at | Western Oregon | 42 | | | None (Unk?) |
| 9/17/2022 | Michigan Tech | 21 | at | Midwestern State | 28 | | | GLIAC |
| Central Washington | 40 | at | Simon Fraser | 7 | | | |
| Eastern New Mexico | 6 | at | Tarleton State | 41 | | | @ WAC (1AA) |
| Angelo State | 34 | at | Texas-Permian Basin | 21 | | | |
| Texas A&M-Kingsville | 31 | at | West Texas A&M | 24 | | | |
| Western Oregon | 30 | at | Western New Mexico | 35 | | | |
| 9/24/2022 | Western New Mexico | 7 | at | Abilene Christian | 34 | | | @ WAC (1AA) |
| West Texas A&M | 14 | at | Angelo State | 34 | | | |
| Simon Fraser | 0 | at | Midwestern State | 77 | | | |
| Eastern New Mexico | 10 | at | Texas A&M-Kingsville | 43 | | | |
| Texas-Permian Basin | 27 | at | Western Oregon | 24 | | | |
| 10/1/2022 | Central Washington | 45 | at | Eastern New Mexico | 17 | | | |
| Texas A&M-Kingsville | 35 | at | Simon Fraser | 7 | | | |
| Texas-Permian Basin | 27 | at | West Texas A&M | 28 | | | |
| Midwestern State | 27 | at | Western New Mexico | 30 | | | |
| Angelo State | 30 | at | Western Oregon | 7 | | | |
| 10/8/2022 | Eastern New Mexico | 9 | at | Angelo State | 28 | | | |
| Western Oregon | 16 | at | Central Washington | 14 | | | |
| West Texas A&M | 38 | at | Midwestern State | 26 | | | |
| Western New Mexico | 17 | at | Texas A&M-Kingsville | 21 | | | |
| Simon Fraser | 24 | at | Texas-Permian Basin | 31 | OT | | |
| 10/15/2022 | Midwestern State | 10 | at | Central Washington | 17 | | | |
| Simon Fraser | 14 | at | Eastern New Mexico | 42 | | | |
| Texas-Permian Basin | 10 | at | Texas A&M-Kingsville | 13 | | | |
| Angelo State | 52 | at | Western New Mexico | 13 | | | |
| West Texas A&M | 13 | at | Western Oregon | 27 | | | |
| 10/22/2022 | Texas A&M-Kingsville | 7 | at | Angelo State | 34 | | | |
| Western New Mexico | 38 | at | Simon Fraser | 21 | | | |
| Midwestern State | 24 | at | Texas-Permian Basin | 23 | | | |
| Central Washington | 16 | at | West Texas A&M | 35 | | | |
| Eastern New Mexico | 7 | at | Western Oregon | 46 | | | |
| 10/29/2022 | Texas A&M-Kingsville | 19 | at | Central Washington | 23 | | | |
| Texas-Permian Basin | 24 | at | Eastern New Mexico | 21 | | | |
| Western Oregon | 21 | at | Midwestern State | 26 | | | |
| Angelo State | 24 | at | Simon Fraser | 0 | | | |
| West Texas A&M | 37 | at | Western New Mexico | 41 | | | |
| 11/5/2022 | Central Washington | 12 | at | Angelo State | 22 | | | |
| Midwestern State | 41 | at | Texas A&M-Kingsville | 37 | | | |
| Western New Mexico | 14 | at | Texas-Permian Basin | 37 | | | |
| Eastern New Mexico | 24 | at | West Texas A&M | 21 | | | |
| Simon Fraser | 7 | at | Western Oregon | 32 | | | |
| 11/12/2022 | Texas-Permian Basin | 14 | at | Central Washington | 49 | | | |
| Western New Mexico | 38 | at | Eastern New Mexico | 24 | | | |
| Angelo State | 37 | at | Midwestern State | 19 | | | |
| West Texas A&M | 14 | at | Simon Fraser | 46 | | | |
| Western Oregon | 48 | at | Texas A&M-Kingsville | 37 | | | |
| 11/26/2022 | Bemidji State | 7 | at | Angelo State | 33 | | D2 Playoffs Round 2 | NSIC |
| 12/3/2022 | Colorado Mines | 42 | at | Angelo State | 24 | | D2 Quarterfinals | RMAC |
| East Central | 38 | vs | Texas A&M-Kingsville | 21 | | Corsicana TX | vs GAC |