| 8/29/2019 | North Carolina Central | 10 | at | Austin Peay | 41 | MEAC | ||
| Eastern Illinois | 10 | at | Chattanooga | 24 | @ SoCon | |||
| Valparaiso | 7 | at | Eastern Kentucky | 53 | Pio | |||
| Pikeville | 20 | at | Murray State | 59 | MSC (NAIA) | |||
| Jacksonville State | 14 | at | Southeastern Louisiana | 35 | @ SLC | |||
| Southern Illinois | 26 | at | SE Missouri State | 44 | MVC | |||
| Northwestern State | 20 | at | Tennessee-Martin | 42 | SLC | |||
| 8/31/2019 | Mississippi Valley State | 20 | at | Tennessee State | 26 | SWAC | ||
| Samford | 58 | at | Tennessee Tech | 59 | 2OT | SoCon | ||
| 9/7/2019 | Central Arkansas | 24 | at | Austin Peay | 16 | SLC | ||
| Tennessee-Martin | 0 | at | Florida | 45 | @ SEC (1A) | |||
| Murray State | 17 | at | Georgia | 63 | @ SEC (1A) | |||
| Eastern Illinois | 0 | at | Indiana | 52 | @ B10 (1A) | |||
| Chattanooga | 20 | at | Jacksonville State | 41 | SoCon | |||
| Eastern Kentucky | 0 | at | Louisville | 42 | @ ACC (1A) | |||
| Tennessee Tech | 17 | at | Miami-Ohio | 48 | @ MAC (1A) | |||
| Tennessee State | 26 | at | Middle Tenn State | 45 | @ CUSA (1A) | |||
| SE Missouri State | 17 | at | Montana State | 38 | @ BSky | |||
| 9/14/2019 | Illinois State | 21 | at | Eastern Illinois | 3 | MVC | ||
| Eastern Kentucky | 7 | at | Indiana State | 19 | @ MVC | |||
| Eastern Washington | 45 | at | Jacksonville State | 49 | BSky | |||
| Austin Peay | 48 | at | Mercer | 34 | @ SoCon | |||
| SE Missouri State | 0 | at | Missouri | 50 | @ SEC (1A) | |||
| Tennessee-Martin | 14 | at | Southern Illinois | 28 | @ MVC | |||
| Jackson State | 49 | vs | Tennessee State | 44 | Memphis TN | vs SWAC | ||
| Virginia-Wise | 14 | at | Tennessee Tech | 31 | SAC (D2) | |||
| Murray State | 0 | at | Toledo | 45 | @ MAC (1A) | |||
| 9/21/2019 | Austin Peay | 14 | at | East Tennessee St | 20 | @ SoCon | ||
| Eastern Illinois | 6 | at | Indiana State | 16 | @ MVC | |||
| North Alabama | 12 | at | Jacksonville State | 30 | BigS | |||
| Morehead State | 7 | at | Murray State | 59 | Pio | |||
| Eastern Kentucky | 35 | at | Presbyterian | 10 | @ BigS | |||
| West Virginia State | 10 | at | SE Missouri State | 56 | MtnE (D2) | |||
| Ark Pine Bluff | 37 | at | Tennessee State | 31 | SWAC | |||
| Tennessee Tech | 38 | at | Western Illinois | 24 | @ MVC | |||
| 9/28/2019 | Jacksonville State | 33 | at | Austin Peay | 52 | |||
| Tennessee Tech | 40 | at | Eastern Illinois | 29 | ||||
| Tennessee State | 16 | at | Eastern Kentucky | 42 | ||||
| Murray State | 7 | at | Tennessee-Martin | 40 | ||||
| 10/5/2019 | Tennessee-Martin | 38 | at | Eastern Kentucky | 28 | |||
| Tennessee State | 23 | at | Jacksonville State | 31 | ||||
| Eastern Illinois | 17 | at | Murray State | 24 | ||||
| Tennessee Tech | 37 | at | SE Missouri State | 43 | ||||
| 10/12/2019 | SE Missouri State | 24 | at | Austin Peay | 28 | |||
| Jacksonville State | 28 | at | Eastern Illinois | 20 | ||||
| Murray State | 31 | at | Tennessee State | 17 | ||||
| Tennessee-Martin | 55 | at | Tennessee Tech | 14 | ||||
| 10/19/2019 | SE Missouri State | 24 | at | Jacksonville State | 21 | |||
| Eastern Kentucky | 34 | at | Murray State | 27 | ||||
| Austin Peay | 24 | at | Tennessee State | 26 | ||||
| Eastern Illinois | 18 | at | Tennessee-Martin | 27 | ||||
| 10/26/2019 | Eastern Kentucky | 33 | at | Eastern Illinois | 6 | |||
| Murray State | 12 | at | Jacksonville State | 14 | ||||
| Tennessee-Martin | 10 | at | SE Missouri State | 17 | ||||
| Austin Peay | 58 | at | Tennessee Tech | 21 | ||||
| 11/2/2019 | Austin Peay | 28 | at | Eastern Kentucky | 21 | OT | ||
| Tennessee Tech | 17 | at | Murray State | 7 | ||||
| SE Missouri State | 32 | at | Tennessee State | 13 | ||||
| Jacksonville State | 17 | at | Tennessee-Martin | 22 | ||||
| 11/9/2019 | Tennessee-Martin | 24 | at | Austin Peay | 38 | |||
| Eastern Kentucky | 31 | at | SE Missouri State | 38 | ||||
| Eastern Illinois | 49 | at | Tennessee State | 38 | ||||
| Jacksonville State | 27 | at | Tennessee Tech | 37 | ||||
| 11/16/2019 | SE Missouri State | 26 | at | Eastern Illinois | 12 | |||
| Tennessee Tech | 10 | at | Eastern Kentucky | 22 | ||||
| Austin Peay | 42 | at | Murray State | 7 | ||||
| Tennessee State | 17 | at | Tennessee-Martin | 28 | ||||
| 11/23/2019 | Eastern Illinois | 7 | at | Austin Peay | 35 | |||
| Eastern Kentucky | 29 | at | Jacksonville State | 23 | ||||
| Tennessee-Martin | 7 | at | Kentucky | 50 | @ SEC (1A) | |||
| Murray State | 24 | at | SE Missouri State | 31 | ||||
| Tennessee State | 37 | at | Tennessee Tech | 27 | ||||
| 11/30/2019 | Furman | 6 | at | Austin Peay | 42 | 1AA Playoffs Round 1 | SoCon | |
| Illinois State | 24 | at | SE Missouri State | 6 | 1AA Playoffs Round 1 | MVC | ||
| 12/7/2019 | Austin Peay | 42 | at | Sacramento State | 28 | 1AA Playoff Round 2 | @ BSky | |
| 12/13/2019 | Austin Peay | 10 | at | Montana State | 24 | 1AA Quarterfinal | @ BSky |