| 8/31/2019 | Middle Tenn State | 21 | at | Michigan (9-4) | 40 | at B10 | ||
| 9/7/2019 | Tennessee State (3-9) | 26 | at | Middle Tenn State | 45 | OVC (1AA) | ||
| 9/14/2019 | Duke (5-7) | 41 | at | Middle Tenn State | 18 | ACC | ||
| 9/28/2019 | Middle Tenn State | 3 | at | Iowa (10-3) | 48 | at B10 | ||
| 10/5/2019 | Marshall (8-5,6-2) | 13 | at | Middle Tenn State | 24 | |||
| 10/12/2019 | Middle Tenn State | 13 | at | Florida Atlantic (11-3,8-1) | 28 | |||
| 10/19/2019 | Middle Tenn State | 30 | at | North Texas (4-8,3-5) | 33 | |||
| 10/26/2019 | Florida Intl (6-7,3-5) | 17 | at | Middle Tenn State | 50 | |||
| 11/2/2019 | Middle Tenn State | 20 | at | UNC-Charlotte (7-6,5-3) | 34 | |||
| 11/16/2019 | Rice (3-9,3-5) | 31 | at | Middle Tenn State | 28 | |||
| 11/23/2019 | Old Dominion (1-11,0-8) | 17 | at | Middle Tenn State | 38 | |||
| 11/30/2019 | Middle Tenn State | 26 | at | Western Kentucky (9-4,6-2) | 31 |
| vs Middle Tenn State | vs Other Opponents | Middle Tenn State compared to OOs | |
| Record: | 8-4 | 68-72 | |
| Points Scored: | 29.92 | 26.35 | -3.57 |
| Points Allowed: | 26.33 | 25.99 | 0.34 |
| Margin: | 3.59 | 0.36 | -3.23 |
| Total Points: | 56.25 | 52.34 | 3.91 |