| 8/29/2019 | Southern Illinois | 26 | at | SE Missouri State (9-4) | 44 | at OVC | ||
| 9/7/2019 | Southern Illinois | 45 | at | Massachusetts (1-11) | 20 | at Ind | ||
| 9/14/2019 | Tennessee-Martin (7-5) | 14 | at | Southern Illinois | 28 | OVC | ||
| 9/21/2019 | Southern Illinois | 28 | at | Arkansas State (8-5) | 41 | at SBC | ||
| 10/5/2019 | Southern Illinois | 10 | at | South Dakota State (8-5,5-4) | 28 | |||
| 10/12/2019 | Illinois State (10-5,5-4) | 21 | at | Southern Illinois | 7 | |||
| 10/19/2019 | Youngstown State (6-6,2-6) | 10 | at | Southern Illinois | 35 | |||
| 10/26/2019 | Southern Illinois | 48 | at | South Dakota (5-7,4-4) | 28 | |||
| 11/2/2019 | Southern Illinois | 23 | at | Indiana State (5-7,3-5) | 14 | |||
| 11/9/2019 | Missouri State (1-10,1-7) | 14 | at | Southern Illinois | 37 | |||
| 11/16/2019 | Southern Illinois | 45 | at | Western Illinois (1-11,1-7) | 21 | |||
| 11/23/2019 | North Dakota State (16-0,9-0) | 21 | at | Southern Illinois | 7 |
| vs Southern Illinois | vs Other Opponents | Southern Illinois compared to OOs | |
| Record: | 5-7 | 72-69 | |
| Points Scored: | 23.00 | 26.24 | 3.24 |
| Points Allowed: | 28.25 | 27.22 | 1.03 |
| Margin: | -5.25 | -0.98 | 4.27 |
| Total Points: | 51.25 | 53.46 | -2.21 |