| 9/5/2019 | West Virginia State | 20 | at | Frostburg State (8-3,7-3) | 17 | | | |
| 9/14/2019 | Glenville State (7-4,6-4) | 30 | at | West Virginia State | 33 | | | |
| 9/21/2019 | West Virginia State | 10 | at | SE Missouri State (9-4) | 56 | | | at OVC |
| 9/28/2019 | West Virginia State | 33 | at | Concord (1-10,1-9) | 23 | | | |
| 10/5/2019 | West Liberty (5-6,4-6) | 29 | at | West Virginia State | 39 | | | |
| 10/12/2019 | West Virginia State | 42 | at | Fairmont State (5-5,5-5) | 38 | | | |
| 10/19/2019 | Urbana (7-4,7-3) | 35 | at | West Virginia State | 31 | | | |
| 10/26/2019 | West Virginia State | 39 | at | West Virginia Wesleyan (1-10,1-9) | 36 | | | |
| 11/2/2019 | Charleston WV (8-3,7-3) | 49 | at | West Virginia State | 24 | | | |
| 11/9/2019 | West Virginia State | 24 | at | Wheeling Jesuit (1-10,1-9) | 0 | | | |
| 11/16/2019 | Notre Dame OH (12-2,9-1) | 31 | at | West Virginia State | 14 | | | |