| 9/1/2019 | Bethune-Cookman (7-4) | 36 | vs | Jackson State | 15 | Atlanta GA | MEAC | |
| 9/7/2019 | Jackson State | 14 | at | South Alabama (2-10) | 37 | at SBC | ||
| 9/14/2019 | Jackson State | 49 | vs | Tennessee State (3-9) | 44 | Memphis TN | vs OVC | |
| 9/28/2019 | Jackson State | 25 | vs | Kentucky State (6-3) | 33 | Indianapolis IN | vs SIAC | |
| 10/5/2019 | Grambling (6-5,6-3) | 44 | at | Jackson State | 21 | |||
| 10/12/2019 | Alabama State (5-6,4-3) | 31 | at | Jackson State | 16 | |||
| 10/19/2019 | Jackson State | 31 | at | Mississippi Valley State (2-9,1-6) | 28 | OT | ||
| 10/24/2019 | Jackson State | 38 | at | Prairie View (6-5,4-3) | 35 | 2OT | ||
| 11/2/2019 | Ark Pine Bluff (6-5,3-4) | 12 | at | Jackson State | 21 | |||
| 11/9/2019 | Jackson State | 43 | at | Alabama A&M (7-5,4-4) | 48 | |||
| 11/16/2019 | Southern (8-5,6-2) | 40 | at | Jackson State | 34 | |||
| 11/23/2019 | Alcorn State (9-4,7-1) | 41 | at | Jackson State | 6 |
| vs Jackson State | vs Other Opponents | Jackson State compared to OOs | |
| Record: | 8-4 | 59-66 | |
| Points Scored: | 35.75 | 26.71 | -9.04 |
| Points Allowed: | 26.08 | 27.47 | -1.39 |
| Margin: | 9.67 | -0.76 | -10.43 |
| Total Points: | 61.83 | 54.18 | 7.65 |