| 8/31/2019 | Missouri | 31 | at | Wyoming (8-5) | 37 | at MW | ||
| 9/7/2019 | West Virginia (5-7) | 7 | at | Missouri | 38 | B12 | ||
| 9/14/2019 | SE Missouri State (9-4) | 0 | at | Missouri | 50 | OVC (1AA) | ||
| 9/21/2019 | South Carolina (4-8,3-5) | 14 | at | Missouri | 34 | |||
| 10/5/2019 | Troy (5-7) | 10 | at | Missouri | 42 | SBC | ||
| 10/12/2019 | Mississippi (4-8,2-6) | 27 | at | Missouri | 38 | |||
| 10/19/2019 | Missouri | 14 | at | Vanderbilt (3-9,1-7) | 21 | |||
| 10/26/2019 | Missouri | 7 | at | Kentucky (8-5,3-5) | 29 | |||
| 11/9/2019 | Missouri | 0 | at | Georgia (12-2,7-2) | 27 | |||
| 11/16/2019 | Florida (11-2,6-2) | 23 | at | Missouri | 6 | |||
| 11/23/2019 | Tennessee (8-5,5-3) | 24 | at | Missouri | 20 | |||
| 11/29/2019 | Missouri | 24 | at | Arkansas (2-10,0-8) | 14 |
| vs Missouri | vs Other Opponents | Missouri compared to OOs | |
| Record: | 6-6 | 73-66 | |
| Points Scored: | 19.42 | 26.48 | 7.06 |
| Points Allowed: | 25.33 | 24.30 | 1.03 |
| Margin: | -5.91 | 2.18 | 8.09 |
| Total Points: | 44.75 | 50.78 | -6.03 |