| 9/1/2018 | Jackson State | 7 | at | Southern Miss (6-5) | 55 | at CUSA | ||
| 9/8/2018 | Jackson State | vs | Tennessee State (4-5) | CCD Memphis TN | vs OVC | |||
| 9/15/2018 | Jackson State | 18 | at | Florida A&M (6-5) | 16 | at MEAC | ||
| 9/29/2018 | Alabama A&M (6-5,5-3) | 21 | at | Jackson State | 16 | |||
| 10/6/2018 | Jackson State | 30 | at | Ark Pine Bluff (2-9,1-6) | 27 | |||
| 10/13/2018 | Mississippi Valley State (1-10,1-6) | 7 | at | Jackson State | 23 | |||
| 10/20/2018 | North Alabama (7-3) | 24 | at | Jackson State | 7 | Ind1AA | ||
| 10/27/2018 | Jackson State | 7 | at | Southern (7-4,6-2) | 41 | |||
| 11/3/2018 | Prairie View (5-6,4-3) | 28 | at | Jackson State | 34 | |||
| 11/10/2018 | Jackson State | 20 | at | Alabama State (4-7,3-4) | 2 | |||
| 11/17/2018 | Jackson State | 3 | at | Alcorn State (9-4,8-1) | 24 |
| vs Jackson State | vs Other Opponents | Jackson State compared to OOs | |
| Record: | 5-5 | 52-58 | |
| Points Scored: | 24.50 | 26.70 | 2.20 |
| Points Allowed: | 16.50 | 29.86 | -13.36 |
| Margin: | 8.00 | -3.16 | -11.16 |
| Total Points: | 41.00 | 56.56 | -15.56 |