| 9/1/2018 | Tuskegee (5-5) | 20 | at | Alabama State | 26 | OT | SIAC (D2) | |
| 9/8/2018 | Alabama State | 9 | at | Auburn (8-5) | 63 | at SEC | ||
| 9/15/2018 | Alabama State | 13 | at | Kennesaw St (11-2) | 62 | at BigS | ||
| 9/22/2018 | Alabama State | 0 | at | Grambling (6-5,5-3) | 34 | |||
| 10/6/2018 | Alabama State | 28 | at | Alcorn State (9-4,8-1) | 25 | 5OT | ||
| 10/13/2018 | Alabama State | 7 | at | South Alabama (3-9) | 45 | at SBC | ||
| 10/27/2018 | Alabama State | 10 | vs | Alabama A&M (6-5,5-3) | 27 | Birmingham AL | ||
| 11/3/2018 | Texas Southern (2-9,1-7) | 21 | at | Alabama State | 30 | |||
| 11/10/2018 | Jackson State (5-5,4-3) | 20 | at | Alabama State | 2 | |||
| 11/17/2018 | Alabama State | 13 | at | Prairie View (5-6,4-3) | 66 | |||
| 11/22/2018 | Mississippi Valley State (1-10,1-6) | 24 | at | Alabama State | 31 | OT |
| vs Alabama State | vs Other Opponents | Alabama State compared to OOs | |
| Record: | 7-4 | 54-61 | |
| Points Scored: | 37.00 | 26.96 | -10.04 |
| Points Allowed: | 15.36 | 26.99 | -11.63 |
| Margin: | 21.64 | -0.03 | -21.67 |
| Total Points: | 52.36 | 53.95 | -1.59 |