| 9/1/2018 | Miles (5-6) | 0 | at | Alabama A&M | 37 | SIAC (D2) | ||
| 9/8/2018 | North Alabama (7-3) | 25 | at | Alabama A&M | 20 | Ind1AA | ||
| 9/15/2018 | Alabama A&M | 7 | at | Cincinnati (11-2) | 63 | at AAC | ||
| 9/22/2018 | Southern (7-4,6-2) | 29 | vs | Alabama A&M | 27 | Mobile AL | ||
| 9/29/2018 | Alabama A&M | 21 | at | Jackson State (5-5,4-3) | 16 | |||
| 10/6/2018 | Alabama A&M | 42 | at | Texas Southern (2-9,1-7) | 21 | |||
| 10/13/2018 | Alcorn State (9-4,8-1) | 35 | at | Alabama A&M | 26 | |||
| 10/27/2018 | Alabama State (4-7,3-4) | 10 | vs | Alabama A&M | 27 | Birmingham AL | ||
| 11/3/2018 | Alabama A&M | 45 | at | Ark Pine Bluff (2-9,1-6) | 14 | |||
| 11/10/2018 | Grambling (6-5,5-3) | 29 | at | Alabama A&M | 16 | |||
| 11/17/2018 | Alabama A&M | 42 | at | Mississippi Valley State (1-10,1-6) | 14 |
| vs Alabama A&M | vs Other Opponents | Alabama A&M compared to OOs | |
| Record: | 5-6 | 54-58 | |
| Points Scored: | 23.27 | 25.28 | 2.01 |
| Points Allowed: | 28.18 | 28.83 | -0.65 |
| Margin: | -4.91 | -3.55 | 1.36 |
| Total Points: | 51.45 | 54.11 | -2.66 |