| 9/3/2016 | Midwestern State (8-3) | 31 | at | Truman State | 19 | LSC | ||
| 9/10/2016 | Malone (1-8) | 3 | at | Truman State | 35 | GLIAC | ||
| 9/17/2016 | Truman State | 44 | at | Missouri S&T (5-6,4-4) | 20 | |||
| 9/24/2016 | Lincoln MO (1-10,0-8) | 0 | at | Truman State | 37 | |||
| 10/1/2016 | Indianapolis (6-5,5-3) | 17 | at | Truman State | 24 | |||
| 10/8/2016 | Truman State | 26 | at | Southwest Baptist (10-2,7-1) | 16 | |||
| 10/15/2016 | Truman State | 3 | at | Grand Valley State (12-1) | 41 | at GLIAC | ||
| 10/22/2016 | William Jewell (1-9,1-7) | 24 | at | Truman State | 31 | |||
| 10/29/2016 | Quincy (5-6,3-5) | 28 | at | Truman State | 38 | |||
| 11/5/2016 | Truman State | 23 | at | St Joseph's (5-6,3-5) | 3 | |||
| 11/12/2016 | Truman State | 14 | at | McKendree (8-3,6-2) | 41 |
| vs Truman State | vs Other Opponents | Truman State compared to OOs | |
| Record: | 3-8 | 59-51 | |
| Points Scored: | 20.36 | 29.44 | 9.08 |
| Points Allowed: | 26.73 | 27.99 | -1.26 |
| Margin: | -6.37 | 1.45 | 7.82 |
| Total Points: | 47.09 | 57.43 | -10.34 |