| 9/3/2016 | Taylor (4-7) | 33 | at | Malone | 39 | OT | MSFA (NAIA) | |
| 9/10/2016 | Malone | 3 | at | Truman State (8-3) | 35 | at GLV | ||
| 9/17/2016 | Notre Dame OH (9-2) | 49 | at | Malone | 21 | MtnE | ||
| 9/24/2016 | Malone | 19 | at | Robert Morris (2-9) | 21 | at NE | ||
| 10/1/2016 | Malone | 10 | at | St Francis PA (7-5) | 52 | at NE | ||
| 10/8/2016 | Alderson-Broaddus (7-2) | 35 | at | Malone | 16 | D2Ind | ||
| 10/22/2016 | Malone | 21 | at | Walsh (1-10,1-10) | 24 | |||
| 11/5/2016 | Malone | 30 | at | Kentucky Wesleyan (3-8) | 40 | at D2Ind | ||
| 11/12/2016 | Malone | 7 | at | West Alabama (7-4) | 56 | at GSC |
| vs Malone | vs Other Opponents | Malone compared to OOs | |
| Record: | 8-1 | 40-49 | |
| Points Scored: | 38.33 | 22.38 | -15.95 |
| Points Allowed: | 18.44 | 26.83 | -8.39 |
| Margin: | 19.89 | -4.45 | -24.34 |
| Total Points: | 56.77 | 49.21 | 7.56 |