| 9/1/2016 | Tiffin (8-3,7-3) | 7 | at | Grand Valley State | 45 | | | |
| 9/10/2016 | Lake Erie (0-11,0-11) | 7 | at | Grand Valley State | 55 | | | |
| 9/17/2016 | Northern Michigan (3-8,3-7) | 24 | at | Grand Valley State | 50 | | | |
| 9/24/2016 | Grand Valley State | 38 | at | Walsh (1-10,1-10) | 0 | | | |
| 10/1/2016 | Grand Valley State | 24 | at | Ohio Dominican (7-4,7-4) | 21 | | | |
| 10/8/2016 | Ferris State (12-3,10-2) | 23 | at | Grand Valley State | 35 | | | |
| 10/15/2016 | Truman State (8-3) | 3 | at | Grand Valley State | 41 | | | GLV |
| 10/22/2016 | Grand Valley State | 35 | at | Hillsdale (5-5,4-5) | 17 | | | |
| 10/29/2016 | Findlay (6-5,6-5) | 17 | at | Grand Valley State | 28 | | | |
| 11/5/2016 | Grand Valley State | 62 | at | Saginaw Valley State (5-5,5-5) | 56 | 2OT | | |
| 11/12/2016 | Grand Valley State | 24 | at | Wayne State MI (7-4,7-4) | 21 | | | |
| 11/26/2016 | Texas A&M-Commerce (10-2) | 32 | at | Grand Valley State | 55 | | | LSC |
| 12/3/2016 | Ferris State (12-3,10-2) | 47 | at | Grand Valley State | 32 | | D2 Quarterfinal | |