| 9/3/2016 | Northern Illinois | 34 | at | Wyoming (8-6) | 40 | OT | at MW | |
| 9/10/2016 | Northern Illinois | 17 | at | South Florida (11-2) | 48 | at AAC | ||
| 9/17/2016 | San Diego State (11-3) | 42 | at | Northern Illinois | 28 | MW | ||
| 9/24/2016 | Western Illinois (6-5) | 28 | at | Northern Illinois | 23 | MVC (1AA) | ||
| 10/1/2016 | Northern Illinois | 31 | at | Ball State (4-8,1-7) | 24 | |||
| 10/8/2016 | Northern Illinois | 30 | at | Western Michigan (13-1,9-0) | 45 | |||
| 10/15/2016 | Central Michigan (6-7,3-5) | 34 | at | Northern Illinois | 28 | 3OT | ||
| 10/22/2016 | Buffalo (2-10,1-7) | 7 | at | Northern Illinois | 44 | |||
| 11/1/2016 | Bowling Green (4-8,3-5) | 20 | at | Northern Illinois | 45 | |||
| 11/9/2016 | Toledo (9-4,6-2) | 31 | vs | Northern Illinois | 24 | Chicago IL | ||
| 11/16/2016 | Northern Illinois | 31 | at | Eastern Michigan (7-6,4-4) | 24 | OT | ||
| 11/25/2016 | Northern Illinois | 31 | at | Kent State (3-9,2-6) | 21 |
| vs Northern Illinois | vs Other Opponents | Northern Illinois compared to OOs | |
| Record: | 7-5 | 77-64 | |
| Points Scored: | 30.33 | 31.13 | 0.80 |
| Points Allowed: | 30.50 | 29.06 | 1.44 |
| Margin: | -0.17 | 2.07 | 2.24 |
| Total Points: | 60.83 | 60.19 | 0.64 |