| 9/1/2016 | Tennessee-Martin | 7 | at | Cincinnati (4-8) | 28 | at AAC | ||
| 9/10/2016 | Tennessee-Martin | 36 | at | Hawaii (7-7) | 41 | at MW | ||
| 9/17/2016 | Bacone (2-8) | 6 | at | Tennessee-Martin | 84 | CSFL (NAIA) | ||
| 9/24/2016 | Tennessee Tech (5-6,5-3) | 23 | at | Tennessee-Martin | 44 | |||
| 10/1/2016 | Tennessee-Martin | 30 | at | Tennessee State (7-4,4-3) | 34 | |||
| 10/8/2016 | Austin Peay (0-11,0-8) | 31 | at | Tennessee-Martin | 45 | |||
| 10/15/2016 | Tennessee-Martin | 38 | at | Murray State (4-7,4-4) | 31 | |||
| 10/22/2016 | Tennessee-Martin | 6 | at | Georgia State (3-9) | 31 | at SBC | ||
| 10/29/2016 | Eastern Kentucky (3-8,2-6) | 3 | at | Tennessee-Martin | 33 | |||
| 11/5/2016 | Tennessee-Martin | 33 | at | Eastern Illinois (6-5,4-4) | 17 | |||
| 11/12/2016 | SE Missouri State (3-8,3-5) | 10 | at | Tennessee-Martin | 24 | |||
| 11/19/2016 | Tennessee-Martin | 7 | at | Jacksonville State (10-2,7-0) | 33 |
| vs Tennessee-Martin | vs Other Opponents | Tennessee-Martin compared to OOs | |
| Record: | 5-7 | 49-76 | |
| Points Scored: | 24.00 | 25.14 | 1.14 |
| Points Allowed: | 32.25 | 31.37 | 0.88 |
| Margin: | -8.25 | -6.23 | 2.02 |
| Total Points: | 56.25 | 56.51 | -0.26 |