| 9/2/2010 | SE Missouri State 1AA | 10 | @ | Ball State | 27 | ||||
| 9/11/2010 | Liberty 1AA | 27 | @ | Ball State | 23 | ||||
| 9/18/2010 | Ball State | 13 | @ | Purdue | 24 | ||||
| 9/25/2010 | Ball State | 0 | @ | Iowa | 45 | ||||
| 10/2/2010 | Ball State | 31 | @ | Central Michigan | 17 | MAC | |||
| 10/9/2010 | Western Michigan | 45 | @ | Ball State | 16 | MAC | |||
| 10/16/2010 | Eastern Michigan | 41 | @ | Ball State | 38 | OT | MAC | ||
| 10/23/2010 | Ball State | 24 | @ | Toledo | 31 | MAC | |||
| 10/30/2010 | Ball State | 14 | @ | Kent State | 33 | MAC | |||
| 11/6/2010 | Akron | 30 | @ | Ball State | 37 | 2 OT | MAC | ||
| 11/12/2010 | Ball State | 20 | @ | Buffalo | 3 | MAC | |||
| 11/20/2010 | Northern Illinois | 59 | @ | Ball State | 21 | MAC |