| 8/26/2010 | Bemidji State Beavers 24 @ Minot State 7 | |
| 9/4/2010 | Minot State 17 @ Concordia-St Paul Golden Bears 38 | |
| 9/18/2010 | Mayville State Comets 10 @ Minot State 42 | † |
| 9/25/2010 | Valley City State Vikings 3 @ Minot State 34 | † |
| 10/2/2010 | Minot State 19 @ Jamestown Jimmies 14 | † |
| 10/9/2010 | Minot State 35 @ Dakota State Trojans 19 | † |
| 10/16/2010 | South Dakota Tech Jackrabbits 10 @ Minot State 6 | † |
| 10/23/2010 | Minot State 17 @ Black Hills State Yellow Jackets 14 | † |
| 10/30/2010 | Dickinson State Blue Hawks 45 @ Minot State 13 | † |