| 9/4/2010 | Livingstone Blue Bears 0 @ Newberry 55 | |
| 9/11/2010 | Valdosta State Blazers 45 @ Newberry 17 | |
| 9/16/2010 | Newberry 35 @ Samford Bulldogs 38 | |
| 10/2/2010 | Lenoir-Rhyne Bears 36 @ Newberry 40 | † |
| 10/9/2010 | Newberry 63 @ Tusculum Pioneers 56 | † |
| 10/16/2010 | Newberry 36 @ Mars Hill Lions 48 | † |
| 10/23/2010 | Catawba Indians 28 @ Newberry 25 | † |
| 10/30/2010 | Carson-Newman Eagles 35 @ Newberry 13 | † |
| 11/6/2010 | Newberry 31 @ Brevard Tornados 3 | † |
| 11/13/2010 | Wingate Bulldogs 49 @ Newberry 33 | † |