| 9/2/2010 | Rhode Island 0 @ Buffalo Bulls 31 | |
| 9/11/2010 | Rhode Island 25 @ Fordham Rams 27 | |
| 9/18/2010 | New Hampshire Wildcats 25 @ Rhode Island 28 | † |
| 10/2/2010 | Brown Bears 24 @ Rhode Island 27 | |
| 10/9/2010 | Rhode Island 7 @ William & Mary Tribe 26 | † |
| 10/16/2010 | Rhode Island 17 @ Delaware Blue Hens 24 | † |
| 10/23/2010 | Maine Black Bears 28 @ Rhode Island 23 | † |
| 10/30/2010 | Rhode Island 30 @ Towson Tigers 20 | † |
| 11/6/2010 | Villanova Wildcats 14 @ Rhode Island 17 | † |
| 11/13/2010 | Rhode Island 6 @ Richmond Spiders 15 | † |
| 11/20/2010 | Massachusetts Minutemen 34 @ Rhode Island 37 | † |