| Friday, 10 Dec 2010 | |||||||
| CAAF | New Hampshire Wildcats | 3 | @ | Delaware Blue Hens | 16 | ||
| Saturday, 11 Dec 2010 | |||||||
| SWAC | Alabama St Hornets | 6 | vs | Texas Southern Tigers | 11 | Birmingham AL | |
| Villanova Wildcats | 42 | @ | Appalachian St Mountaineers | 24 | |||
| Shepherd Rams (D2) | 17 | @ | Delta St Statesmen (D2) | 29 | |||
| North Dakota St Bison | 31 | @ | Eastern Washington Eagles | 38 | OT | ||
| NW Missouri St Bearcats (D2) (12-1) | @ | Minnesota-Duluth Bulldogs (D2) | 17 | ||||
| Bethel MN Royals (D3) | 14 | @ | Mount Union Purple Raiders (D3) | 34 | |||
| Ind | Army Black Knights | 17 | vs | Navy Midshipmen | 31 | Philadelphia PA | |
| UW-Whitewater Warhawks (D3) | 27 | @ | Wesley Wolverines (D3) | 7 | |||
| SoCon | Georgia Southern Eagles | 23 | @ | Wofford Terriers | 20 | ||