| 9/4/2010 | Franklin @ Carthage | |
| 9/4/2010 | North Central @ Cornell IA | |
| 9/4/2010 | Augustana IL @ Greenville | |
| 9/4/2010 | Illinois Wesleyan @ Hope | |
| 9/4/2010 | Millikin @ Illinois College | |
| 9/4/2010 | Elmhurst @ Loras | |
| 9/4/2010 | Aurora @ North Park | |
| 9/11/2010 | Wheaton @ Albion | |
| 9/11/2010 | Central IA @ Augustana IL | |
| 9/11/2010 | Alma @ Illinois Wesleyan | |
| 9/11/2010 | Carthage @ Lakeland | |
| 9/11/2010 | Ill. Benedictine @ North Park | |
| 9/11/2010 | Elmhurst @ Olivet | |
| 9/18/2010 | Augustana IL @ Adrian | |
| 9/18/2010 | Illinois Wesleyan @ Aurora | |
| 9/18/2010 | Carthage @ Concordia WI | |
| 9/18/2010 | Chicago @ Elmhurst | |
| 9/18/2010 | Hope @ Millikin | |
| 9/18/2010 | MacMurray @ North Park | |
| 9/18/2010 | North Central @ Olivet | |
| 9/18/2010 | Wisconsin-Platteville @ Wheaton | |
| 9/25/2010 | Greenville @ Millikin | |
| 9/25/2010 | Wisconsin-Eau Claire @ North Central | |
| 9/25/2010 | Wheaton @ Olivet | |
| 10/2/2010 | Augustana IL @ Millikin | † |
| 10/2/2010 | Carthage @ North Central | † |
| 10/2/2010 | Elmhurst @ North Park | † |
| 10/2/2010 | Illinois Wesleyan @ Wheaton | † |
| 10/9/2010 | North Central @ Augustana IL | † |
| 10/9/2010 | Millikin @ Carthage | † |
| 10/9/2010 | Wheaton @ Elmhurst | † |
| 10/9/2010 | North Park @ Illinois Wesleyan | † |
| 10/16/2010 | Augustana IL @ Carthage | † |
| 10/16/2010 | Elmhurst @ Illinois Wesleyan | † |
| 10/16/2010 | Millikin @ North Central | † |
| 10/16/2010 | North Park @ Wheaton | † |
| 10/23/2010 | Elmhurst @ Millikin | † |
| 10/23/2010 | Illinois Wesleyan @ North Central | † |
| 10/23/2010 | Augustana IL @ North Park | † |
| 10/23/2010 | Carthage @ Wheaton | † |
| 10/30/2010 | Wheaton @ Augustana IL | † |
| 10/30/2010 | North Park @ Carthage | † |
| 10/30/2010 | North Central @ Elmhurst | † |
| 10/30/2010 | Millikin @ Illinois Wesleyan | † |
| 11/6/2010 | Augustana IL @ Elmhurst | † |
| 11/6/2010 | Carthage @ Illinois Wesleyan | † |
| 11/6/2010 | Millikin @ North Park | † |
| 11/6/2010 | North Central @ Wheaton | † |
| 11/13/2010 | Illinois Wesleyan @ Augustana IL | † |
| 11/13/2010 | Elmhurst @ Carthage | † |
| 11/13/2010 | Wheaton @ Millikin | † |
| 11/13/2010 | North Park @ North Central | † |