| 9/4/2010 | Bethel TN Wildcats 31 @ Wisconsin-Eau Claire 35 | |
| 9/11/2010 | St John's MN Johnnies 20 @ Wisconsin-Eau Claire 23 | |
| 9/25/2010 | Wisconsin-Eau Claire 6 @ North Central Cardinals 20 | |
| 10/2/2010 | Wisconsin-Stevens Point Pointers 13 @ Wisconsin-Eau Claire 20 | † |
| 10/9/2010 | Wisconsin-Eau Claire 14 @ Wisconsin-Platteville Pioneers 35 | † |
| 10/16/2010 | Wisconsin-Whitewater Warhawks 45 @ Wisconsin-Eau Claire 0 | † |
| 10/23/2010 | Wisconsin-Eau Claire 28 @ Wisconsin-Stout Blue Devils 37 | † |
| 10/30/2010 | Wisconsin-Oshkosh Titans 14 @ Wisconsin-Eau Claire 20 | † |
| 11/6/2010 | Wisconsin-Eau Claire 14 @ Wisconsin-La Crosse Eagles 49 | † |
| 11/13/2010 | Wisconsin-River Falls Falcons 45 @ Wisconsin-Eau Claire 42 | † |