| 9/3/2009 | Illinois St 6 @ Eastern Illinois 31 | |
| 9/12/2009 | Eastern Illinois 31 @ Indiana St 0 | |
| 9/19/2009 | Eastern Illinois 23 @ SE Missouri St 14 | † |
| 9/26/2009 | Eastern Illinois 30 @ Austin Peay 20 | † |
| 10/3/2009 | Eastern Kentucky 36 @ Eastern Illinois 31 | † |
| 10/10/2009 | Eastern Illinois 3 @ Penn State 52 | |
| 10/17/2009 | Tennessee Tech 15 @ Eastern Illinois 23 | † |
| 10/24/2009 | Eastern Illinois 28 @ Jacksonville St 20 | † |
| 10/31/2009 | Eastern Illinois 16 @ Murray St 10 | † |
| 11/14/2009 | Tennessee-Martin 13 @ Eastern Illinois 49 | † |
| 11/19/2009 | Tennessee St 21 @ Eastern Illinois 10 | † |
| 11/28/2009 | Eastern Illinois 7 @ Southern Illinois 48 (FCS Playoff round 1) |