| 9/3/2009 | Eastern Kentucky 13 @ Indiana 19 | |
| 9/19/2009 | Tennessee Tech 7 @ Eastern Kentucky 17 | † |
| 9/26/2009 | Eastern Kentucky 23 @ Murray St 13 | † |
| 10/3/2009 | Eastern Kentucky 36 @ Eastern Illinois 31 | † |
| 10/10/2009 | Tennessee St 20 @ Eastern Kentucky 17 | † |
| 10/17/2009 | Tennessee-Martin 25 @ Eastern Kentucky 31 | † |
| 10/24/2009 | Eastern Kentucky 20 @ Austin Peay 24 | † |
| 10/31/2009 | SE Missouri St 6 @ Eastern Kentucky 20 | † |
| 11/7/2009 | Eastern Kentucky 12 @ Kentucky 37 | |
| 11/14/2009 | Western Carolina 24 @ Eastern Kentucky 7 | |
| 11/21/2009 | Eastern Kentucky 26 @ Jacksonville St 34 | † |