| 9/3/2009 | Illinois St 6 @ Eastern Illinois 31 | |
| 9/12/2009 | Illinois St 17 @ Illinois 45 | |
| 9/19/2009 | Austin Peay 7 @ Illinois St 38 | |
| 9/26/2009 | S Dakota St 38 @ Illinois St 17 | † |
| 10/3/2009 | Illinois St 27 @ N Dakota St 24 | † |
| 10/10/2009 | Illinois St 23 @ Southern Illinois 43 | † |
| 10/17/2009 | Indiana St 21 @ Illinois St 38 | † |
| 10/31/2009 | Illinois St 24 @ Missouri State 14 | † |
| 11/7/2009 | Western Illinois 7 @ Illinois St 25 | † |
| 11/14/2009 | Illinois St 18 @ Youngstown St 30 | † |
| 11/21/2009 | Northern Iowa 20 @ Illinois St 22 | † |