| 9/5/2005 | Mississippi | 10 | @ | Memphis | 6 | ||||
| 9/17/2005 | Chattanooga | 14 | @ | Memphis | 59 | ||||
| 9/24/2005 | Memphis | 31 | @ | Tulsa | 37 | OT | CUSA | ||
| 10/1/2005 | UTEP | 20 | @ | Memphis | 27 | CUSA | |||
| 10/8/2005 | Memphis | 17 | @ | UCF | 38 | CUSA | |||
| 10/15/2005 | Memphis | 35 | @ | Houston | 20 | CUSA | |||
| 10/22/2005 | East Carolina | 24 | @ | Memphis | 27 | CUSA | |||
| 11/1/2005 | UAB | 37 | @ | Memphis | 20 | CUSA | |||
| 11/12/2005 | Memphis | 16 | @ | Tennessee | 20 | ||||
| 11/19/2005 | Memphis | 24 | @ | Southern Miss | 22 | CUSA | |||
| 11/26/2005 | Marshall | 3 | @ | Memphis | 26 | CUSA | |||
| 12/26/2005 | Memphis | 38 | vs | Akron | 31 | Motor CIty |