| 9/10/2005 | Akron | 24 | @ | Purdue | 49 | ||||
| 9/17/2005 | Akron | 14 | @ | Middle Tenn St | 7 | ||||
| 9/24/2005 | Northern Illinois | 42 | @ | Akron | 48 | OT | MAC | ||
| 10/1/2005 | Central Michigan | 31 | @ | Akron | 17 | MAC | |||
| 10/8/2005 | Akron | 13 | @ | Buffalo | 7 | MAC | |||
| 10/15/2005 | Akron | 23 | @ | Miami-Ohio | 51 | MAC | |||
| 10/22/2005 | Army | 20 | @ | Akron | 0 | ||||
| 10/29/2005 | Akron | 24 | @ | Bowling Green | 14 | MAC | |||
| 11/5/2005 | Akron | 17 | @ | Ball State | 23 | MAC | |||
| 11/15/2005 | Ohio | 3 | @ | Akron | 27 | MAC | |||
| 11/24/2005 | Kent St | 3 | @ | Akron | 35 | MAC | |||
| 12/1/2005 | Akron | 31 | vs | Northern Illinois | 30 | MAC | MAC CG | ||
| 12/26/2005 | Memphis | 38 | vs | Akron | 31 | Motor CIty |