| 9/1/2005 | William & Mary | 24 | @ | Marshall | 36 | ||||
| 9/10/2005 | Kansas St | 21 | @ | Marshall | 19 | ||||
| 9/24/2005 | Marshall | 13 | @ | UCF | 23 | CUSA | |||
| 10/1/2005 | SMU | 13 | @ | Marshall | 16 | OT | CUSA | ||
| 10/8/2005 | Marshall | 14 | @ | #11 Virginia Tech | 41 | ||||
| 10/15/2005 | UAB | 19 | @ | Marshall | 20 | CUSA | |||
| 10/22/2005 | Marshall | 3 | @ | UTEP | 31 | CUSA | |||
| 10/29/2005 | Marshall | 27 | @ | Tulane | 26 | CUSA | |||
| 11/8/2005 | Southern Miss | 27 | @ | Marshall | 24 | OT | CUSA | ||
| 11/19/2005 | East Carolina | 34 | @ | Marshall | 29 | CUSA | |||
| 11/26/2005 | Marshall | 3 | @ | Memphis | 26 | CUSA |