| 9/3/2005 | Rutgers | 30 | @ | Illinois | 33 | OT | |||
| 9/10/2005 | San Jose St | 19 | @ | Illinois | 40 | ||||
| 9/17/2005 | Illinois | 20 | @ | California | 35 | ||||
| 9/24/2005 | Michigan St | 61 | @ | Illinois | 14 | B10 | |||
| 10/1/2005 | Illinois | 7 | @ | #25 Iowa | 35 | B10 | |||
| 10/8/2005 | Illinois | 13 | @ | Indiana | 36 | B10 | |||
| 10/22/2005 | #3 Penn State | 63 | @ | Illinois | 10 | B10 | |||
| 10/29/2005 | #20 Wisconsin | 41 | @ | Illinois | 24 | B10 | |||
| 11/5/2005 | Illinois | 2 | @ | #4 Ohio State | 40 | B10 | |||
| 11/12/2005 | Illinois | 3 | @ | Purdue | 37 | B10 | |||
| 11/19/2005 | Northwestern | 38 | @ | Illinois | 21 | B10 |