| 8/27/2022 | Hastings (7-4) | 28 | at | Trinity International | 0 | GPAC | ||
| 9/8/2022 | Trinity International | 14 | at | Quincy (4-7) | 53 | at GLV | ||
| 9/17/2022 | Trinity International | 19 | at | Taylor (5-6,5-5) | 41 | |||
| 9/24/2022 | Trinity International | 6 | at | Indiana Wesleyan (10-2,9-0) | 63 | |||
| 10/1/2022 | Saint Ambrose (2-8,2-7) | 49 | at | Trinity International | 7 | |||
| 10/8/2022 | Trinity International | 7 | at | St Francis IL (7-3,7-3) | 39 | |||
| 10/15/2022 | Roosevelt (7-3,6-3) | 42 | at | Trinity International | 14 | |||
| 10/22/2022 | St Xavier (9-3,9-1) | 35 | at | Trinity International | 6 | |||
| 10/29/2022 | Trinity International | 10 | at | Missouri Baptist (4-7,3-6) | 24 | |||
| 11/5/2022 | Olivet Nazarene (7-4,6-4) | 27 | at | Trinity International | 14 | |||
| 11/12/2022 | Trinity International | 42 | at | Judson (2-8,2-8) | 32 |
| vs Trinity International | vs Other Opponents | Trinity International compared to OOs | |
| Record: | 10-1 | 54-54 | |
| Points Scored: | 39.36 | 25.40 | -13.96 |
| Points Allowed: | 12.64 | 27.94 | -15.30 |
| Margin: | 26.72 | -2.54 | -29.26 |
| Total Points: | 52.00 | 53.34 | -1.34 |