| 8/27/2022 | Missouri Baptist | 12 | at | Lyon (1-9) | 24 | at Soon | ||
| 9/3/2022 | Iowa Wesleyan (4-7) | 23 | at | Missouri Baptist | 25 | 3OT | NSAA | |
| 9/17/2022 | Missouri Baptist | 44 | at | Madonna (0-11,0-9) | 37 | OT | ||
| 9/24/2022 | Marian IN (9-2,9-1) | 45 | at | Missouri Baptist | 7 | |||
| 10/1/2022 | St Francis IL (7-3,7-3) | 28 | at | Missouri Baptist | 21 | |||
| 10/8/2022 | Missouri Baptist | 3 | at | Roosevelt (7-3,6-3) | 41 | |||
| 10/15/2022 | Missouri Baptist | 13 | at | St Xavier (9-3,9-1) | 31 | |||
| 10/22/2022 | Olivet Nazarene (7-4,6-4) | 37 | at | Missouri Baptist | 30 | |||
| 10/29/2022 | Trinity International (1-10,1-8) | 10 | at | Missouri Baptist | 24 | |||
| 11/5/2022 | Missouri Baptist | 16 | at | Judson (2-8,2-8) | 27 | |||
| 11/12/2022 | Missouri Baptist | 42 | at | Saint Ambrose (2-8,2-7) | 38 |
| vs Missouri Baptist | vs Other Opponents | Missouri Baptist compared to OOs | |
| Record: | 7-4 | 42-64 | |
| Points Scored: | 31.00 | 22.78 | -8.22 |
| Points Allowed: | 21.55 | 30.02 | -8.47 |
| Margin: | 9.45 | -7.24 | -16.69 |
| Total Points: | 52.55 | 52.80 | -0.25 |