| 9/3/2022 | Howard (5-6) | 28 | at | Hampton | 31 | MEAC | ||
| 9/10/2022 | Tuskegee (8-3) | 10 | at | Hampton | 42 | SIAC (D2) | ||
| 9/17/2022 | Hampton | 17 | at | Norfolk State (2-9) | 7 | at MEAC | ||
| 9/24/2022 | Hampton | 3 | at | Delaware (8-5,4-4) | 35 | |||
| 10/8/2022 | Maine (2-9,2-6) | 31 | at | Hampton | 24 | |||
| 10/15/2022 | Hampton | 38 | at | Albany NY (3-8,2-6) | 37 | OT | ||
| 10/22/2022 | Richmond (9-4,6-2) | 41 | at | Hampton | 10 | |||
| 10/29/2022 | Hampton | 10 | at | Villanova (6-5,4-4) | 24 | |||
| 11/5/2022 | William & Mary (11-2,7-1) | 20 | at | Hampton | 14 | |||
| 11/12/2022 | Elon (8-4,6-2) | 38 | at | Hampton | 24 | |||
| 11/19/2022 | Hampton | 7 | at | Towson (6-5,4-4) | 27 |
| vs Hampton | vs Other Opponents | Hampton compared to OOs | |
| Record: | 7-4 | 61-56 | |
| Points Scored: | 27.09 | 26.70 | -0.39 |
| Points Allowed: | 20.00 | 27.36 | -7.36 |
| Margin: | 7.09 | -0.66 | -7.75 |
| Total Points: | 47.09 | 54.06 | -6.97 |