| 9/4/2021 | Morehouse | 7 | at | West Alabama (7-4) | 48 | at GSC | ||
| 9/11/2021 | Morehouse | 0 | at | West Georgia (9-3) | 47 | at GSC | ||
| 9/18/2021 | Miles (6-5,6-3) | 37 | at | Morehouse | 14 | |||
| 9/25/2021 | Morehouse | 10 | at | Savannah State (8-2,6-1) | 29 | |||
| 10/2/2021 | Edward Waters (4-7,3-7) | 37 | at | Morehouse | 13 | |||
| 10/9/2021 | Tuskegee (3-8,3-5) | 15 | vs | Morehouse | 31 | Birmingham AL | ||
| 10/16/2021 | Fort Valley State (5-5,5-4) | 3 | at | Morehouse | 51 | |||
| 10/23/2021 | Morehouse | 20 | at | Benedict (5-5,5-5) | 5 | |||
| 10/30/2021 | Albany State GA (10-2,8-0) | 14 | at | Morehouse | 10 | |||
| 11/6/2021 | Morehouse | 35 | at | Clark Atlanta (2-8,1-7) | 26 |
| vs Morehouse | vs Other Opponents | Morehouse compared to OOs | |
| Record: | 6-4 | 53-45 | |
| Points Scored: | 26.10 | 26.07 | -0.03 |
| Points Allowed: | 19.10 | 22.71 | -3.61 |
| Margin: | 7.00 | 3.36 | -3.64 |
| Total Points: | 45.20 | 48.78 | -3.58 |