| 9/2/2021 | LIU | 10 | at | Florida Intl (1-11) | 48 | at CUSA | ||
| 9/11/2021 | LIU | 0 | at | West Virginia (6-7) | 66 | at B12 | ||
| 9/18/2021 | LIU | 7 | at | Miami-Ohio (7-6) | 42 | at MAC | ||
| 10/9/2021 | LIU | 10 | at | St Francis PA (5-6,4-3) | 55 | |||
| 10/16/2021 | Merrimack (5-6,2-5) | 43 | at | LIU | 5 | |||
| 10/23/2021 | LIU | 30 | at | Central Conn (4-7,4-3) | 13 | |||
| 10/30/2021 | Wagner (0-11,0-7) | 14 | at | LIU | 28 | |||
| 11/6/2021 | Duquesne (7-3,5-2) | 34 | at | LIU | 28 | |||
| 11/13/2021 | LIU | 7 | at | Bryant (7-4,5-2) | 52 | |||
| 11/20/2021 | Sacred Heart (8-4,6-1) | 38 | at | LIU | 14 |
| vs LIU | vs Other Opponents | LIU compared to OOs | |
| Record: | 8-2 | 42-63 | |
| Points Scored: | 40.50 | 22.23 | -18.27 |
| Points Allowed: | 13.90 | 27.30 | -13.40 |
| Margin: | 26.60 | -5.07 | -31.67 |
| Total Points: | 54.40 | 49.53 | 4.87 |